? High Salary: Principal Scientist Quantitative Systems
Company: Sanofi
Location: Cambridge
Posted on: June 25, 2025
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Job Description:
Job Title: Principal Scientist Quantitative Systems Location:
Waltham, MA About the Job Are you ready to shape the future of
medicine? The race is on to speed up drug discovery and development
to find answers for patients and their families. Your skills could
be critical in helping teams accelerate Progress. Join our
Quantitative Systems Pharmacology (QSP) group as a Principal
Scientist and you'll support our R&D portfolio with mechanistic
disease modeling. This position is based in Cambridge, MA. We are
an innovative global healthcare company with one purpose: to chase
the miracles of science to improve people’s lives. We’re also a
company where you can flourish and grow your career, with countless
opportunities to explore, make connections with people, and stretch
the limits of what you thought was possible. Ready to get started?
Main Responsibilities: - Function as part of a team to develop and
apply multiscale computational models of complex diseases based on
detailed biological mechanistic knowledge to support model-informed
drug discovery & development. - Survey literature to gain
understanding of critical physiological processes to be
represented, and identify suitable mechanistic elements, data,
parameters and assumptions to be included. - Identify and analyze
suitable internal preclinical and clinical data to inform modeling
activities. - Analyze simulation results and identify appropriate
strategies to resolve issues pertaining to model performance and
accuracy. - Maintain extensive documentation of model development
process, and data analysis. - Maintain quantitative systems
pharmacology expertise through comprehensive education - undefined
- Communicate modeling predictions to key stakeholders. About You:
- PhD with an excellent track record of productivity in the areas
of systems pharmacology/biology, computational biology, biomedical
engineering or related field, as manifested by publications and
scientific presentations in conferences - At least 2 years of
Postdoctoral experience in disease modeling/QSP - Experience in
drug discovery/development a plus, especially in bioinformatics or
pharmacometrics. - Proficiency in mathematical modeling using
differential equations. - Extensive experience in computational
tools such as MATLAB, Julia and R (MATLAB preferred). - Excellent
oral and written communication skills. - Ability to quickly learn
pathophysiology in indications of interest, and treatment
approaches in immunology. - Highly motivated, detail-oriented, and
independent researcher. - Able to thrive in a collaborative,
multi-disciplinary team environment. - Strong commitment to
on-the-job-training. - undefined Preferred but no required:
Knowledge of Immunology Why Choose Us? - Bring the miracles of
science to life alongside a supportive, future-focused team. -
Discover endless opportunities to grow your talent and drive your
career, whether it’s through a promotion or lateral move, at home
or internationally. - Enjoy a thoughtful, well-crafted rewards
package that recognizes your contribution and amplifies your
impact. - Take good care of yourself and your family, with a wide
range of health and wellbeing benefits including high-quality
healthcare, prevention and wellness programs and at least 14 weeks’
gender-neutral parental leave. Sanofi Inc. and its U.S. affiliates
are Equal Opportunity and Affirmative Action employers committed to
a culturally diverse workforce. All qualified applicants will
receive consideration for employment without regard to race; color;
creed; religion; national origin; age; ancestry; nationality;
marital, domestic partnership or civil union status; sex, gender,
gender identity or expression; affectional or sexual orientation;
disability; veteran or military status or liability for military
status; domestic violence victim status; atypical cellular or blood
trait; genetic information (including the refusal to submit to
genetic testing) or any other characteristic protected by law.
GD-SA LI-SA LI-Onsite vhd All compensation will be determined
commensurate with demonstrated experience. Employees may be
eligible to participate in Company employee benefit programs, and
additional benefits information can be found here.
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