Head of Sales & Account Management, Gene Therapy

Company: uniQure N.V.
Location: Lexington
Posted on: July 1, 2025

Job Description:

uniQure is dedicated to bringing innovative therapies or unmet medical needs to patients. In doing so each function in uniQure is directly or indirectly responsible for the lives of patients. This responsibility should be part of our day-to-day working life by (i) living up to high quality standards and (ii) by recognizing the sense of urgency in areas of high medical need. uniQure is entering into an exciting time with its first ever product launch planned for 2026. uniQure’s lead program, AMT-130, a one-time gene therapy for adult patients with Huntington’s Disease, has received RMAT and Breakthrough Designation from the FDA. The Head of Sales and Account Management will lead the buildout of the Sales and Account Management Leads and develop the Sales and Account Management strategy to effectively launch and drive uptake of AMT-130. The role will closely collaborate and coordinate plans with Commercial (including Marketing, Market Access, and Patient Services) and Medical Affairs. The Sales and Account Management Leads, who report into the Head of Sales and Account Management, will be considered the central coordination lead for treatment center activity, and will be the bridge between strategy with execution; They will serve as the main point of contact for treatment centers pre- and post-onboarding and will execute treatment center activation. Key result areas (major duties, accountabilities and responsibilities) • Contribute to the strategic direction and development of in field executional plans in partnership with the core functional leads. • Lead a team of approximately 4-5 Regional Account Directors, tasked with building their teams and delivering patient and business value. • Ensure team meets or exceeds targets following all compliance expectations. • Develop a strategic plan to outline national and regional objectives including competencies and capabilities. • Lead the sales and account management organization pre-launch and launch planning to support maximum uptake at approval. • Provide input to the Commercial Operations team on design the incentive compensation plan and the call plan, targets, expectations and tracking to effectively measure performance. • Partner with training to develop coaching frameworks and capability to successfully engage in the field. • Collaborate with Marketing, Market Access, Patient Support Services, Commercial Operations, Medical Affairs, Legal, Compliance and other internal stakeholders; monitor progress and drive course correction where necessary. • Establish appropriate U.S. targets and objectives, support definition of key performance indicators (KPIs) and proactively monitor and adjust incentives and metrics to drive success. • Conduct field visits and national team meetings to align teams, monitor execution, identify issues/opportunities and define new actions. Be deeply involved in the recruitment and onboarding of the Sales and Account Directors; Coach and Develop field team members to help support retention of high performers and improve performance of mid-low performers Qualifications • Seasoned commercial leader with 15 years U.S. leadership experience in sales, commercial operations, and/or account management in pharmaceutical / biotech organizations • BA/BS Required • MBA and/or other advanced scientific degree preferred (i.e., MBA, MPH or PharmD). • Previous second line management and U.S. Specialty / Rare / Gene or Cell Therapy product launch and buildout experience preferred. • Working knowledge of how to work within Centers of Excellence and Academic Centers; knowledge of how to compliantly work with case management, field reimbursement, and medical science liaison teams required. • Must be familiar with relevant legal and regulatory environment in biotech/pharmaceutical industry. • Demonstrated knowledge of working total accounts / treatment centers • Proven track record in driving culture of accountability. • Effective planning, prioritization, management, and organizational skills. • Ability to clearly communicate complex messages, accurately. To understand specific needs of intended audience and tailor communication accordingly, detail oriented with ability to understand big picture impact. • Works collaboratively across expertise areas and functions; seeks to advance higher goals; highly regarded across stakeholders both at senior and junior levels; inspires trust at all levels; patient-centric, and passionate for innovation and discovery. • Must be comfortable spending 50% of the time traveling to visit customers, attend conferences and attend meetings in the Lexington (MA) office. • Candidate must have a valid U.S. driver’s license to be considered. • Demonstrated commitment to ethics and integrity.

Keywords: uniQure N.V., Nantucket , Head of Sales & Account Management, Gene Therapy, Sales , Lexington, Massachusetts